(E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole is an organic compound with the chemical formula C18H17N5O2.
Nature:
This compound is a yellow crystal, soluble in organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane, but hardly soluble in water. Its melting point is about 132-134°C. This compound is the (E) stereoisomer and is optically active.
Use:
(E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole can be used as an important intermediate in organic synthesis. It can be used to synthesize various heterocyclic compounds, such as natural products and drugs.
Preparation Method:
The preparation method of (E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole is relatively complicated. One commonly used method is synthesis by the catalytic coupling reaction of a cyanide catalyst and a naphthalene ring.
Safety Information:
For specific safety information about (E)-6-nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole, it is also necessary to refer to relevant chemical databases and literature for search and evaluation. In general, chemicals are toxic and dangerous, so it is necessary to follow the relevant laboratory safety procedures when using and handling the compound.